Factor eight inhibiting bypass activity for refractory bleeding in acute type A aortic dissection repair: A propensity-matched analysis.
Stevan S PupovacRandy LevineAshley T GiammarinoSamuel Jacob ScheinermanAlan R HartmanDerek R BrinsterJonathan M HemliPublished in: Transfusion (2022)
When used as rescue therapy for refractory bleeding following repair of ATAAD, FEIBA appears to be effective in decreasing postoperative transfusion requirements whilst not negatively impacting clinical outcomes. These findings should prompt further investigation and validation via larger, multi-center, randomized trials.