TCF3 gene rearrangements in pediatric B-cell acute lymphoblastic leukemia-A single center experience.

Svetlana LebedevaYaroslav MenchitsAlexandra BorkovskaiaSophia SokolovaOlga SoldatkinaEkaterina MikhailovaAlexander M PopovAlexander KomkovYulia RumiantsevaAlexander KarachunskiiYulia Olshanskaya

Published in: International journal of laboratory hematology (2023)

So, high molecular heterogeneity of TCF3 gene rearrangement in pediatric BCP-ALL was demonstrated and a novel fusion gene TCF3::TLX1 was described.

Keyphrases

acute lymphoblastic leukemia
copy number
genome wide
genome wide identification
single cell
allogeneic hematopoietic stem cell transplantation