Evaluation of Pancreatic VMAT2 Binding with Active and Inactive Enantiomers of [18F]FP-DTBZ in Healthy Subjects and Patients with Type 1 Diabetes.
Mika NaganawaKeunpoong LimNabeel B NabulsiShu-Fei LinDavid LabareeJim RopchanKevan C HeroldYiyun HuangPaul HarrisMasanori IchiseGary W ClineRichard E CarsonPublished in: Molecular imaging and biology (2019)
Non-displaceable uptake was different among organs and between enantiomers. Use of scaled spleen VT values for VND is a suitable method for quantification of VMAT2 in the pancreas.