Dose-volume metrics and their relation to memory performance in pediatric brain tumor patients: A preliminary study.
Kimberly P RaghubarMichael LambaKim M CecilKeith Owen YeatesE Mark MahoneChristina LimkeDavid GrosshansTravis J BeckwithM Douglas RisPublished in: Pediatric blood & cancer (2018)
These preliminary findings call into question the value of prescribed dose for characterizing treatment intensity; they also suggest that biophysical dose has only a limited advantage compared to physical dose when calculated for specific regions of the brain. We discuss the implications of the findings for evaluating and understanding the relation between RT and neurocognitive functioning.