A role for telomere length and chromosomal damage in idiopathic pulmonary fibrosis.

John E McDonoughDries S MartensNaoya TanabeFarida AhangariStijn E VerledenKaren MaesGeert M VerledenNaftali KaminskiJames C HoggTim S NawrotWim A WuytsBart M Vanaudenaerde

Published in: Respiratory research (2018)

Telomere length and chromosomal damage are involved in IPF with regional variation in telomere length and chromosomal damage associated with pathological changes in tissue structure and the extracellular matrix.

Keyphrases

idiopathic pulmonary fibrosis
extracellular matrix
oxidative stress
copy number
interstitial lung disease
gene expression