Clinical characteristics and surgical outcome in USP8-mutated human adrenocorticotropic hormone-secreting pituitary adenomas.

Marco LosaPietro MortiniAngela PagnanoMario DetomasMaria Francesca CassarinoFrancesca Pecori Giraldi

Published in: Endocrine (2018)

ACTH-secreting pituitary adenomas carrying somatic USP8 mutations are associated with a greater likelihood of surgical remission in patients operated by a single neurosurgeon. Recurrence rates are not related with USP8-variant status.

Keyphrases

end stage renal disease
endothelial cells
chronic kidney disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
growth hormone
gene expression
copy number
systemic lupus erythematosus
patient reported outcomes