Nitroxide-enhanced MRI of cardiovascular oxidative stress.
Soham A ShahSophia X CuiChristopher D WatersSoichi SanoYing WangHeather DoviakJonathan LeorKenneth WalshBrent A FrenchFrederick H EpsteinPublished in: NMR in biomedicine (2020)
Nitroxide-enhanced MRI noninvasively quantifies tissue oxidative stress as one component of a multiparametric preclinical MRI examination. These methods may facilitate investigations of oxidative stress in cardiovascular disease and related therapies.
Keyphrases
- oxidative stress
- contrast enhanced
- magnetic resonance imaging
- cardiovascular disease
- dna damage
- diffusion weighted imaging
- diabetic rats
- ischemia reperfusion injury
- induced apoptosis
- type diabetes
- computed tomography
- stem cells
- magnetic resonance
- mesenchymal stem cells
- metabolic syndrome
- coronary artery disease
- bone marrow
- signaling pathway