Preclinical tests for salicylhydrazones derivatives to explore their potential for new antituberculosis agents.
Andressa Lorena IequeCarolina Trevisolli PalomoVitória Gabriela de Freitas SpanholMaria Luiza Fróes da Motta DacomeJosé Júnior do Carmo PereiraFrancielli Cavalcante CandidoKatiany Rizzieri Caleffi-FerracioliVera Lucia Dias SiqueiraRosilene Fressatti CardosoFábio VandresenVanessa Guimarães Alves-OlherRegiane Bertin de Lima ScodroPublished in: Tuberculosis (Edinburgh, Scotland) (2024)
All salicylhydrazones showed potential in the screening tests performed in this study and compound 18 stood out due to its activity against susceptible and resistant bacilli at low concentrations and low cytotoxicity.