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In severe acne vulgaris, TNF-α gene variants are connected to increased TNF-α gene expression and insulin resistance.

Ahmed Ibrahim AbdElneamSharif AlhajlahMohammed Saleh Al-DhubaibiSaleh Salem BahajGhada Farouk MohammedAhmed Kaid AlantryLina Mohammed Atef
Published in: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) (2024)
There is a correlation between AV, especially severe acne, and the -863 G > A and -308 G > A polymorphism, which influences TNF-α gene expression and serum TNF-α levels.
Keyphrases
  • gene expression
  • rheumatoid arthritis
  • insulin resistance
  • dna methylation
  • copy number
  • early onset
  • type diabetes
  • metabolic syndrome
  • high fat diet
  • skeletal muscle
  • polycystic ovary syndrome
  • high fat diet induced