Gut Microbiota in Patients with Morbid Obesity Before and After Bariatric Surgery: a Ten-Year Review Study (2009-2019).
Spyridon G KoulasChristos K StefanouStefanos K StefanouKostas TepelenisNikolaos ZikosKonstantinos TepetesAndreas KapsoritakisPublished in: Obesity surgery (2020)
The changes in the composition and function of gut microbiota affect the metabolic functions (which are mediated by microbial effects) in patients with obesity, resulting in significant physiological regulation in these patients. Most of the studies emphasize that the Western-style diet (high fat and low vegetable consumption) leads to significant changes in the intestinal microbiome in individuals with metabolic syndrome. A deeper understanding of the profiles of gut microbes will contribute to the development of new therapeutic strategies for the management of metabolic syndrome and other metabolic diseases and related disorders. The aim of this review is to evaluate recent experimental evidence outlining the alterations of gut microbiota composition and function in recovery from bariatric surgical operations with an emphasis on sleeve gastrectomy and gastric bypass.
Keyphrases
- metabolic syndrome
- weight loss
- gastric bypass
- bariatric surgery
- roux en y gastric bypass
- insulin resistance
- obese patients
- end stage renal disease
- uric acid
- newly diagnosed
- type diabetes
- ejection fraction
- chronic kidney disease
- weight gain
- high fat diet induced
- physical activity
- prognostic factors
- peritoneal dialysis
- cardiovascular disease
- south africa
- adipose tissue
- body mass index
- patient reported