Neoadjuvant radiation improves margin-negative resection rates in extremity sarcoma but not survival.
Rita D ShelbyLorena P Suarez-KellyPeter Y YuTasha M HughesCecilia G EthunThuy B TranGeorge PoultsidesDavid M KingMeena BediHarveshp MogalCallisia N ClarkeJennifer TsengKevin K RogginKonstantinos ChouliarasKonstantinos VotanopoulosBradley A KrasnickRyan C FieldsRaphael E PollockJ Harrison HowardKenneth CardonaValerie GrignolPublished in: Journal of surgical oncology (2020)
In this large study, radiotherapy improved limb salvage rates and decreased local recurrences. Receipt of NAR achieves more margin-negative resections however this did not improve local recurrence or survival rates over.