A mini-whole lung lavage to treat autoimmune pulmonary alveolar proteinosis (PAP).
Francesca MarianiElena SalvaterraSara LettieriAnnalisa De SilvestriAlessandra CorinoMatteo BosioElia FraoliniDavide PiloniGiuseppe RodiAngelo Guido CorsicoIlaria CampoPublished in: Respiratory research (2022)
Mini-WLL has demonstrated higher efficacy in ameliorating lung volumes, suggesting that a lower infusion volume is sufficient to remove the surfactant accumulation and possibly allows a reduced mechanical insult of the bronchi walls and the alveoli. However, no statistically significant differences were found in terms of DLCO% and Aa-O2.