Scavenger receptors mediate increased uptake of irradiated T.gondii extracts by J774 macrophages.

Andrea da CostaCamila Aparecida de CarvalhoNanci do NascimentoHeitor Franco de Andrade

Published in: International journal of radiation biology (2023)

Our data suggests that cell SRs recognize irradiated proteins, mainly SRs for oxidized proteins, leading to antigen uptake by an intracytoplasmic pathway with fewer peptidases that prolongs presentation to nascent major histocompatibility complex I or II and enhances immunity by better antigen presentation.

Keyphrases

single cell
case report
cell therapy
electronic health record
big data
stem cells
machine learning
mesenchymal stem cells
deep learning