Patisiran Enhances Muscle Mass after Nine Months of Treatment in ATTRv Amyloidosis: A Study with Bioelectrical Impedance Analysis and Handgrip Strength.

Vincenzo Di Stefano Ewan ThomasPaolo AlongeValerio Giustino Guglielmo PillitteriIgnazio LealeAngelo Torrente Antonia Pignolo Davide Norata Salvatore Iacono Antonino Lupica Antonio Palma Giuseppe BattagliaFilippo Brighina

Published in: Biomedicines (2022)

BIA might represent a useful tool to assess the effects of multiorgan damage in ATTRv and to monitor disease progression and response to treatments. More evidence is still needed for HGS. Patisiran stabilizes polyneuropathy and preserves motor strength by increasing muscle mass after 9 months of treatment.

Keyphrases

oxidative stress
body composition
magnetic resonance imaging
combination therapy
replacement therapy
data analysis
contrast enhanced