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Association of 5p15.2 and 15q14 with high myopia in Tujia and Miao Chinese populations.

Junwen WangFang LiuXiusheng SongTuo Li
Published in: BMC ophthalmology (2020)
Our meta-analysis results show that rs634990 was significantly associated with myopia but that rs6885224 was not. Nevertheless, in our replication study, these two SNPs showed no association with myopia in the Tujia and Miao Chinese populations. This is the first report involving Tujia and Miao ethnic groups from Enshi minority areas. However, the sample size needs to be expanded and more stringent inclusion and exclusion criteria need to be formulated to verify the findings.
Keyphrases
  • systematic review
  • optic nerve
  • genome wide
  • meta analyses
  • genetic diversity
  • gene expression
  • dna methylation