Direct oral challenge for immediate and non-immediate beta-lactam allergy in children: A real-world multicenter study.

Luis Moral Teresa ToralCandelaria MuñozNuria MarcoBelén García-AvilésLaura MurciaMaría José ForniésMaría Cristina GonzálezFrancisco CanalsEsther Bragado Javier Martínez Olmos Carlos García-MagánJosé Domingo Moure GonzálezNuria CortésMagalí GiménezCatalina GómezAna Belén RodríguezAna MorenoJosé Manuel LucasSergio QuevedoCristina BlascoYolanda Aliaga

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2024)

Direct oral DPT is a safe, effective procedure even in immediate mild reactions to BLA. Many reactions observed in DPT are doubtful and require confirmation. Severe reactions are exceptional and amenable to treatment. Direct oral DPT can be considered for BLA allergy delabeling in pediatric primary care.

Keyphrases

primary care
young adults
early onset
escherichia coli
gram negative