Influence of common SCN1A promoter variants on the severity of SCN1A-related phenotypes.

Iris M de LangeWout WeuringRuben van 't SlotBoudewijn GunningAnja C M SonsmaMark McCormackCarolien de KovelLisette J J M van GemertFlip MulderMarjan J A van KempenNine V A M KnoersEva H BrilstraBobby P C Koeleman

Published in: Molecular genetics & genomic medicine (2019)

The nonsignificant observed trends in our study warrant replication studies in larger cohorts to explore the potential modifying role of these common SCN1A promoter-haplotypes.

Keyphrases

dna methylation
transcription factor
gene expression
copy number
climate change
human health