Real-World Incidence of Breakthrough Coronavirus Disease 2019 Hospitalization After Vaccination vs Natural Infection in a Large, Local, Empaneled Primary Care Population Using Time-to-Event Analysis.

Benjamin D PollockCurtis B StorlieAaron J TandePriya Sampathkumar

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2022)

We followed 106 349 primary care patients for 22 385 3099 person-days across 21 calendar months and documented 69 breakthrough coronavirus disease 2019 (COVID-19) hospitalizations: 65/102,613 (0.06%) among those fully vaccinated, 3/11 047 (0.03%) among those previously infected, and 1/7,313 (0.01%) among those with both statuses. These data give providers real-world context regarding breakthrough COVID-19 hospitalization risk.

Keyphrases

coronavirus disease
primary care
end stage renal disease
respiratory syndrome coronavirus
ejection fraction
newly diagnosed
sars cov
chronic kidney disease
risk factors
peritoneal dialysis
prognostic factors
electronic health record
machine learning
artificial intelligence