Long-term administration of sirolimus does not affect the physical development of children with tuberous sclerosis complex.
Jian ChenWen HeYang-Yang WangMeng-Na ZhangQian LuQiu-Hong WangXiao-Mei LuoBin WangLi-Ping ZouPublished in: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery (2022)
Overactivation of the mTOR pathway and long-term administration of sirolimus does not affect the physical development of children with TSC.