Prenatal Diagnosis of Congenital Heart Diseases and Associations with Serum Biomarkers of Aneuploidy: A Multicenter Prospective Cohort Study.

Jeong Ha Wie You-Jung Han Soo-Hyun Kim Moon-Young Kim Hee Young Cho Mi-Young Lee Jin Hoon Chung Seung Mi Lee Soo Young Oh Joon Ho Lee Hye Yeon Boo Geum Joon Cho Han-Sung Kwon Byoung Jae Kim Mi Hye Park Hyun Mee Ryu Hyun Sun Ko

Published in: Yonsei medical journal (2022)

Ultrasonography performed during the second trimester by obstetricians detected over 85% of critical CHDs. Low maternal serum PAPP-A or high inhibin-A was associated with non-chromosomal CHDs. These results may contribute to an improvement in prenatal diagnosis of CHDs.

Keyphrases

pregnancy outcomes
magnetic resonance imaging
preterm birth
copy number
computed tomography
gestational age
body mass index