Extrastriatal dopaminergic and serotonergic pathways in Parkinson's disease and in dementia with Lewy bodies: a 123I-FP-CIT SPECT study.
Andrea PilottoFrancesca Schiano di ColaEnrico PremiRoberto GrassoRosanna TurroneStefano GipponiAndrea ScalviniElisabetta CottiniBarbara PagheraValentina GaribottoMaria Cristina RizzettiLaura BonanniBarbara BorroniSilvia MorbelliFlavio NobiliUgo Paolo GuerraDaniela PeraniAlessandro PadovaniPublished in: European journal of nuclear medicine and molecular imaging (2019)
PD and DLB patients both showed insular dopamine deficits, whereas impairment of thalamic serotonergic pathways was specifically associated with DLB. Longitudinal studies are necessary to determine the clinical value of the assessment of extrastriatal 123I-FP-CIT SPECT.