Cholecalciferol Exhibits no Antibacterial Effect on Staphylococcus aureus and Escherichia coli : An in vitro Study.

Shilia Jacob KurianAvirup BiswasShrivathsa KulavalliJesil Mathew AranjaniAmrita PattanaikMurali MunisamyKavitha SaravuGabriel Sunil RodriguesSonal Sekhar Miraj

Published in: Recent advances in anti-infective drug discovery (2024)

This study indicates that cholecalciferol does not directly inhibit S. aureus and E. coli. Hence, we suggest exploring the antibacterial properties of other vitamin D analogs, such as calcitriol or its synergetic effect with other antimicrobial agents.

Keyphrases

escherichia coli
staphylococcus aureus
biofilm formation
silver nanoparticles
molecular docking
anti inflammatory
klebsiella pneumoniae
molecular dynamics simulations
structure activity relationship