Vascular endothelial-cadherin as a marker of endothelial injury in preclinical Alzheimer disease.
Rawan M TarawnehRachel S KasperJessie SanfordChia-Ling PhuahJason HassenstabCarlos CruchagaPublished in: Annals of clinical and translational neurology (2022)
Our results support the utility of CSF VEC as a marker of endothelial injury in AD and highlight the importance of endothelial injury as an early pathology that contributes to cognitive impairment in even the earliest preclinical stages.