Analysis of Caspase-9 protein and microRNAs miR-21, miR-126 and miR-155 related to the apoptosis mechanism in the cerebellum of rats submitted to focal cerebral ischemia associated with an alcoholism model.
Jairo Pinheiro da SilvaFermino Sanches Lizarte NetoMucio Luiz de Assis CirinoCamila Albuquerque Melo de CarvalhoCarlos Gilberto CarlottiBenedicto Oscar ColliDaniela Pretti da Cunha TirapelliLuís Fernando TirapelliPublished in: Arquivos de neuro-psiquiatria (2019)
We conclude that apoptosis occurs in the cerebellar cortex, even if it is distant from the ischemic focus, and that microRNAs 126 and 155 show a correlation with cellular apoptosis in ischemic rats and those submitted to the chronic alcohol model.