CDH17 nanobodies facilitate rapid imaging of gastric cancer and efficient delivery of immunotoxin.

Jingbo MaXiaolong XuChunjin FuPeng XiaMing TianLiuhai ZhengKun ChenXiaolian LiuYilei LiLe YuQinchang ZhuYangyang YuRongrong FanHaibo JiangZhifen LiChuanbin YangChengchao XuYing LongJigang WangZhijie Li

Published in: Biomaterials research (2022)

The study presents a novel imaging and drug delivery strategy by targeting CDH17. CDH17 nanobody-based immunotoxin is potentially a promising therapeutic modality for clinical translation against gastric cancer.

Keyphrases

drug delivery
high resolution
fluorescence imaging
mass spectrometry
drug release
loop mediated isothermal amplification