JAZF1 heterozygous knockout mice show altered adipose development and metabolism.

Jain JeongSoyoung JangSong ParkWookbong KwonSi-Yong KimSoyoen JangJiwon KoSi Jun ParkSu-Geun LimDuhak YoonJunkoo YiSanggyu LeeMyoung Ok KimSeong-Kyoon ChoiZae Young Ryoo

Published in: Cell & bioscience (2021)

Our findings emphasized the JAZF1 role in adipocyte differentiation and related metabolism through the heterozygous knockout mice. This study provides new insights into the JAZF1 function in adipose development and metabolism, informing strategies for treating obesity and related metabolic disorders.

Keyphrases

insulin resistance
adipose tissue
early onset
metabolic syndrome
type diabetes
weight loss
high fat diet induced
weight gain