A multi-mode Wnt- and stemness-regulatory module dictated by FOXM1 and ASPM isoform I in gastric cancer.

Chung-Chi HsuWen-Ying LiaoKwang-Yu ChangTze-Sian ChanPo-Jui HuangChun-Ting ChiangYan-Shen ShanLin-Hsin ChengTai-Yan LiaoKelvin K Tsai

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2021)

This study illuminates a novel Wnt- and stemness-regulatory mechanism in GC cells and identifies a novel subset of FOXM1highASPMiIhigh GC with potential to guide Wnt- and stemness-related diagnostics and therapies.

Keyphrases

stem cells
epithelial mesenchymal transition
cell proliferation
induced apoptosis
transcription factor
cell cycle arrest
cancer stem cells
genome wide
oxidative stress
signaling pathway
endoplasmic reticulum stress
gene expression
dna methylation
mass spectrometry
climate change
tandem mass spectrometry