Assessment of the impact of EHR heterogeneity for clinical research through a case study of silent brain infarction.

Sunyang FuLester Y LeungAnne-Olivia RaulliDavid F KallmesKristin A KinsmanKristoff B NelsonMichael S ClarkPatrick H LuetmerPaul R KingsburyDavid M KentHongfang Liu

Published in: BMC medical informatics and decision making (2020)

The implementation of the framework identified the institutional and process variations and the heterogeneity of EHRs across the sites participating in the case study. The experiment demonstrates the necessity to have a standardized process for data abstraction when conducting EHR-based clinical studies.

Keyphrases

electronic health record
single cell
primary care
healthcare
resting state
white matter
quality improvement
big data
functional connectivity
blood brain barrier
brain injury