Diagnostic Accuracy of FEC-PET/CT, FDG-PET/CT, and Diffusion-Weighted MRI in Detection of Nodal Metastases in Surgically Treated Endometrial and Cervical Carcinoma.
Andrea G RockallTara D BarwickWilliam WilsonNaveena SinghNishat BharwaniAslam SohaibMarielle NobbenhuisVictoria WarbeyMarc E MiquelDow-Mu KohKatja N De PaepePierre L Martin-HirschSadaf Ghaem-MaghamiChristina FotopoulouHelen StringfellowSudha SundarRanjit ManchandaAnju SahdevAllan HackshawGary J R Cooknull nullPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
All imaging techniques had low sensitivity for detection of nodal metastases and cannot replace surgical nodal staging. The performance of FEC-PET/CT was not statistically different from other techniques that are more widely available. FDG-PET/CT had higher sensitivity than size in detecting nodal metastases. False positive rates were low across all methods. The low false positive rate demonstrated by FDG-PET/CT may be helpful in arbitration of challenging surgical planning decisions.