A reversible, colorimetric, pH-responsive indole-based hydrogel and its application in urea detection.
Yan WangXuan LuoLongfei ZhangShuai ZhangLin ZhangPublished in: RSC advances (2019)
A new type of pH-responsive indole-based (4-HINF) hydrogel, fabricated by a sol-gel method, was utilized as a platform for colorimetric detection of urea in aqueous solution. The colorimetric sensor was established by virtue of the synergistic effect of cation-π interaction and hydrogen bonding with good regenerative ability. The results exhibited linear response in the range of 0-10 mM with a limit of detection of 10 μM. The prepared 4-HINF hydrogel possessed high selectivity to pH change under complicated environments ensuring further applications in environmental and bio-systems.
Keyphrases
- aqueous solution
- gold nanoparticles
- label free
- loop mediated isothermal amplification
- drug delivery
- sensitive detection
- hydrogen peroxide
- tissue engineering
- hyaluronic acid
- real time pcr
- fluorescent probe
- wound healing
- stem cells
- living cells
- mesenchymal stem cells
- high throughput
- cancer therapy
- nitric oxide
- risk assessment
- single cell
- cell therapy
- ionic liquid