Reperfused vs. nonreperfused myocardial infarction: when to use which model.
Merry L LindseyLisandra E de Castro BrásKristine Y DeLeon-PennellNikolaos G FrangogiannisGanesh V HaladeCaitlin C O'MearaFrancis G SpinaleZamaneh KassiriJonathan A KirkPetra KleinbongardCrystal M RipplingerKeith R BruntPublished in: American journal of physiology. Heart and circulatory physiology (2021)
There is a lack of understanding in the cardiac remodeling field regarding the use of nonreperfused myocardial infarction (MI) and reperfused MI in animal models of MI. This Perspectives summarizes the consensus of the authors regarding how to select the optimum model for your experiments and is a part of ongoing efforts to establish rigor and reproducibility in cardiac physiology research.