Treatment of recalcitrant cases of tinea corporis/cruris caused by T. mentagrophytes - interdigitale complex with mutations in ERG11 ERG 3, ERG4, MDR1 MFS genes & SQLE and their potential implications.

Anamika BhattacharyyaSuresh SadhasivamMau SinhaSwati GuptaSwamini SainiHimanshi SinghAnanta KhuranaSoumya SachdevaKabir SardanaShamik Ghosh

Published in: International journal of dermatology (2023)

Our findings demonstrate possible reasons for multidrug resistance in the prevalent strain with mutations in genes that predict terbinafine (SQLE) and azole actions (ERG4, ERG11, ERG3) apart from efflux pumps (MDR1, MFS) that can explain multidrug clinical failures.

Keyphrases

multidrug resistant
genome wide
dna methylation
transcription factor
candida albicans
human health
smoking cessation