Intermittent inhibition of FYVE finger-containing phosphoinositide kinase induces melanosome degradation in B16F10 melanoma cells.

Kyoka KawaguchiMiyu WatanabeSaho FurukawaKenichi KogaHiromitsu KanamoriMitsushi J IkemotoShigeo TakashimaMiwa MaedaKentaro Oh-HashiYoko HirataKyoji FurutaHiroshi Takemori

Published in: Molecular biology reports (2023)

In conclusion, disturbance of PIKfyve activity induces melanosome degradation in a canonical autophagy-independent manner.

Keyphrases

cell death
endoplasmic reticulum stress
signaling pathway
oxidative stress
protein kinase