DNA primase subunit 1 deteriorated progression of hepatocellular carcinoma by activating AKT/mTOR signaling and UBE2C-mediated P53 ubiquitination.
Mengqi ZhuMengna WuSaiyan BianQianqian SongMingbing XiaoHua HuangLi YouJianping ZhangJie ZhangChun ChengWenkai NiWenjie ZhengPublished in: Cell & bioscience (2021)
This study implies that PRIM1 may play a key role in the progression of HCC and may serve as a potential target for HCC treatment.