Model Informed Development of SIM0295 in Patients with Gout and Hyperuricemia and Healthy Volunteers Using a Population Pharmacokinetics/ Pharmacodynamics Approach.

Yue-Ting ChenYang YangShansen XuChen-Yu WangPan ShuXiaoyu ZhangQin HuangJin Sook KimZheng Jiao

Published in: Expert opinion on investigational drugs (2023)

The established popPK/PD model characterized the dose-exposure-response relationship for SIM0295 in healthy subjects and patients with gout and hyperuricemia and could be used to inform the drug development.

Keyphrases

uric acid
metabolic syndrome