Primary prophylaxis in children with severe haemophilia A and B-Implementation over the last 20 years as illustrated in real-world data in the PedNet cohorts.

Rolf C R Ljung Marloes de Kovel H Marijke van den Bergnull null

Published in: Haemophilia : the official journal of the World Federation of Hemophilia (2022)

Primary prophylaxis nowadays starts at an earlier age: before any joint bleed (60% of patients with SHA and SHB). Approximately 70% started on a once-weekly schedule with significantly reduced doses in SHA but unchanged in SHB.

Keyphrases

primary care
young adults
electronic health record
big data
quality improvement
machine learning
deep learning
data analysis