p38α in the preoptic area inhibits brown adipose tissue thermogenesis.
Jing WangShanshan WuHuidong ZhanWenkai BiYang XuYixiao LiangYueping GeLi PengXinchen JinKeke LuJiajun ZhaoLing GaoZhao HePublished in: Obesity (Silver Spring, Md.) (2022)
These results demonstrate that p38α in the POA exacerbates obesity development, at least in part owing to a decrease in BAT thermogenesis.