A simplified transposon mutagenesis method to perform phenotypic forward genetic screens in cultured cells.
Charlotte R FeddersenLexy S WadsworthEliot Y ZhuHayley R VaughnAndrew P VoigtJesse D RiordanAdam J DupuyPublished in: BMC genomics (2019)
Collectively, our work establishes a facile, adaptable method that can be performed by labs of any size to perform robust, genome-wide screens to identify genes that influence phenotypes of interest.