Opioid Receptor Mu 1 Gene (OPRM1) A118G Polymorphism and Emotional Modulation of Pain.

Edward A TrimbleParker A KellMatteo A AvellaChristopher R FranceJamie L Rhudy

Published in: Journal of pain research (2024)

The altered response to pleasant stimuli further supports the role of opioids in appetitive behavior and describes how the A118G polymorphism may prevent carriers from inhibiting pain during pleasure.

Keyphrases

chronic pain
pain management
neuropathic pain
signaling pathway
copy number
dna methylation
genome wide identification