MR Imaging Differences in the Circle of Willis between Healthy Children and Adults.
Kristin P GuilliamsN GuptaS SrinivasanMichael M BinkleyChunwei YingL CoutureJ GrossAdam N WallaceRobert C McKinstryKatie D VoJin-Moo LeeHongyu AnManu S GoyalPublished in: AJNR. American journal of neuroradiology (2021)
Our results demonstrate that the circle of Willis is different in size and symmetry in healthy children compared with adults, likely associated with developmental changes in cerebral perfusion. Further work is needed to understand why asymmetric vasculature develops in some but not all adults.