Prevalence of the DPYD variant (Y186C) in Brazilian individuals of African ancestry.

Geraldo Felício Cunha-JuniorLuciana Bastos-RodriguesPedro G AzevedoMaria Aparecida BicalhoLuiz Alexandre V MagnoLuiz De MarcoLuiz Gonzaga Coelho

Published in: Cancer chemotherapy and pharmacology (2019)

The variant Y186C is prevalent among Brazilians of African ancestry and should be taken in account in targeted genotyping for fluoropyrimidine risk variants.

Keyphrases

genome wide association study
risk factors
genome wide
copy number
high throughput
genetic diversity