Helicobacter pylori-controlled c-Abl localization promotes cell migration and limits apoptosis.
Gernot PosseltMaria WiesauerBianca E ChichirauDaniela EnglerLinda M KrischGabriele GadermaierPeter BrizaSabine SchneiderFrancesco BoccellatoThomas F MeyerCornelia Hauser-KronbergerDaniel NeureiterAnne MüllerSilja WesslerPublished in: Cell communication and signaling : CCS (2019)
In this study, we identified a novel regulatory mechanism in Hp-infected gastric epithelial cells by which Hp determines the subcellular localization of activated c-Abl to control Hp-mediated EMT-like processes while decreasing cell death.