Effect of positive surgical margins at radical prostatectomy on cancer-specific mortality in high/very high-risk prostate cancer patients with Gleason Grade Group 4-5.
Antonio Benito PorcaroGabriele SorceBenedikt HoehLukas HohenhorstStefano TapperoNancy NimerPaweł RajwaZhe TianCarlo TerroneFelix K H ChunAlberto BrigantiFred SaadShahrokh F ShariatMaria Angela CerrutoAlessandro AntonelliPierre I KarakiewiczPublished in: The Prostate (2022)
In HR/VHR PCa patients with exclusive GGG 4-5, PSM at RP adversely affect survival. Moreover, RT has no protective effect on CSM. In consequence, lowest possible PSM rates are crucial in such patients.