Ziwuliuzhu Acupuncture Modulates Clock mRNA, Bmal1 mRNA and Melatonin in Insomnia Rats.

Ao Huang Gefang Xiao Yiliu Chen Zuying Hu Pin-Hsuan Lee Yusen Huang Zifeng Zhuang Yuling Zhang Peng Qing Canghuan Zhao

Published in: Journal of acupuncture and meridian studies (2023)

Ziwuliuzhu acupuncture alleviated neuronal damage and modulated the inflammatory reaction in the hypothalamus of rats with insomnia. Moreover, Ziwuliuzhu acupuncture increased the expression levels of Clock and Bmal1 mRNA, and MT content. This study has potentially highlighted one of the mechanisms through which Ziwuliuzhu acupuncture can be used to treat insomnia.

Keyphrases

binding protein
sleep quality
oxidative stress
brain injury
long non coding rna
cerebral ischemia
electron transfer