Acute kidney injury in children with moderate-severe COVID-19 and multisystem inflammatory syndrome in children: a referral center experience.

Tugba Tastemel Ozturk Ali Düzova Pembe Derin Oygar Demet Baltu Pelin Ozcilingir Hakverdi Sibel Lacinel Gurlevik Eda Didem Kurt Sukur Hakan Hayrettin Aykan Seher Sener İlker Ertuğrul Selman Kesici Bora Gülhan Fatih Ozaltin Yasemin Özsürekci Ali Bulent Cengiz Rezan Topaloğlu

Published in: Pediatric nephrology (Berlin, Germany) (2023)

Independent risk factors for AKI were need for vasoactive/inotropic agents and vomiting/diarrhea in moderate, severe or critical COVID-19 patients; and need for vasoactive/inotropic agents and severe inflammation in MIS-C patients. Our findings suggest that inflammation and cardiac dysfunction are associated with AKI in MIS-C patients; and the association with age in this group merits further studies in larger groups. Early outcome is favorable; long-term follow-up for kidney functions is needed. A higher resolution version of the Graphical abstract is available as Supplementary information.

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