Nickel allergy is associated with a broad spectrum cytokine response.
Niels P J De GraafSanne RoffelSusan GibbsCornelis Johannes KleverlaanMarta Lopez GonzalezThomas RustemeyerAlbert J FeilzerEsther J NossentPublished in: Contact dermatitis (2022)
A broad spectrum of 33 cytokines and chemokines is involved in the allergen-specific immune response in nickel allergic patients. IL-5 remains, next to the lymphocyte proliferation test, the strongest biomarker for nickel allergy.