Management and outcomes of acute respiratory distress syndrome patients with and without comorbid conditions.

Elie AzoulayVirginie LemialeBruno MourvillierMaite Garrouste-OrgeasCarole SchwebelStéphane RucklyLaurent ArgaudYves CohenBertrand SouweineLaurent PapazianJean ReignierGuillaume MarcotteShidasp SiamiHatem KallelMichael DarmonJean-François Timsitnull null

Published in: Intensive care medicine (2018)

Half the patients with ARDS had major comorbidities, which were associated with severe ARDS, multiple organ dysfunction, and day-28 mortality. These findings do not support the exclusion of ARDS patients with severe comorbidities from randomized clinical trials. Trials in ARDS patients with whatever comorbidities are warranted.

Keyphrases

acute respiratory distress syndrome
extracorporeal membrane oxygenation
mechanical ventilation
early onset
oxidative stress
intensive care unit
cardiovascular events
risk factors
clinical trial
type diabetes
adipose tissue
drug induced
cardiovascular disease
metabolic syndrome
double blind
weight loss