Ginger and avocado as nutraceuticals for obesity and its comorbidities.
Natalia Dos Santos TramontinThais F LucianoScherolin de Oliveira MarquesClaudio Teodoro de SouzaAlexandre Pastoris MullerPublished in: Phytotherapy research : PTR (2020)
Obesity is a worldwide epidemic and is one of the factors involved in the etiology of type 2 diabetes mellitus. Obesity induces low-grade inflammation and oxidative stress. The treatment for obesity involves changes in diet, physical activity, and even medication and surgery. Currently, the use of nutraceutical compounds is associated with health benefits. Ginger and avocado are used for many people all around the world; however, its effect as a nutraceutical compound is less known by the general population. For this reason, we searched information of the literature to point its effects on distinct mechanisms of defense against the obesity its comorbidities. The present review aimed showing that these nutraceuticals may be useful in obesity treatment. Reports have shown that ginger and avocado induce antioxidant and anti-inflammatory effects by improving enzymatic activity and modulating obesity-related impairments in the anti-inflammatory system in different tissues, without side effects. Furthermore, ginger and avocado were found to be effective in reversing the harmful effects of obesity on blood lipids. In conclusion, on the basis of the positive effects of ginger and avocado in in vitro, animal, and human studies, these nutraceuticals may be useful in obesity treatment.
Keyphrases
- weight loss
- insulin resistance
- metabolic syndrome
- type diabetes
- high fat diet induced
- weight gain
- oxidative stress
- physical activity
- low grade
- healthcare
- systematic review
- endothelial cells
- anti inflammatory
- adipose tissue
- emergency department
- public health
- gene expression
- ischemia reperfusion injury
- high grade
- minimally invasive
- mental health
- skeletal muscle
- dna damage
- health information
- nitric oxide
- heat stress
- endoplasmic reticulum stress
- coronary artery bypass
- adverse drug
- social media
- innate immune