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Bacille Calmette Guerin (BCG) and prevention of types 1 and 2 diabetes: Results of two observational studies.

Hans F DiasYoshihiko MochizukiWillem M KühtreiberHiroyuki TakahashiHui ZhengDenise L Faustman
Published in: PloS one (2023)
The epidemiological evidence analyzed here suggests that BCG may play a role in the prevention of T1D. It does not support prevention of T2D, most likely because of interference by metformin. Our ecological analysis of global data suggests a role for neonatal BCG in the prevention of T1D and, to a lesser extent, T2D. Randomized clinical trials are needed to confirm these findings.
Keyphrases
  • type diabetes
  • clinical trial
  • climate change
  • metabolic syndrome
  • electronic health record
  • skeletal muscle
  • insulin resistance
  • deep learning
  • double blind