Early marker of ocular neurodegeneration in children and adolescents with type 1 diabetes: the contributing role of polymorphisms in mir146a and mir128a genes.

Claudia PionaSilvia CostantiniChiara ZusiTiziano CozziniEmilio PedrottiMarco MariglianoElena FornariAlice MaguoloAnita MorandiClaudio Maffeis

Published in: Acta diabetologica (2022)

These results provide new insight into the genetic predisposition to DN showing that two polymorphisms in MIR146A and MIR128A genes could significantly contribute to the development of early ocular preclinical signs of DN.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
genome wide
mesenchymal stem cells
transcription factor